Yutong Zhao Selected Research

Lung Injury

5/2024	Indole-3-Acetic Acid Protects Against Lipopolysaccharide-induced Endothelial Cell Dysfunction and Lung Injury through the Activation of USP40.
2/2024	The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β.
1/2019	The HECT ubiquitin E3 ligase Smurf2 degrades μ-opioid receptor 1 in the ubiquitin-proteasome system in lung epithelial cells.
6/2017	Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation.
8/2016	Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.
7/2015	Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis.
12/2013	Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.
7/2013	Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
6/2012	F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation.
10/2011	Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.

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Yutong Zhao Research Topics

Disease

20	Inflammation (Inflammations) 05/2024 - 02/2006
14	Lung Injury 05/2024 - 04/2009
14	Neoplasms (Cancer) 01/2024 - 02/2014
10	Infections 03/2021 - 10/2003
10	Acute Lung Injury 01/2021 - 09/2009
8	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2024 - 12/2013
8	Fibrosis (Cirrhosis) 03/2024 - 01/2013
7	Pneumonia (Pneumonitis) 03/2021 - 10/2011
6	Asthma (Bronchial Asthma) 01/2021 - 04/2007
6	Sepsis (Septicemia) 06/2017 - 01/2011
5	Lung Neoplasms (Lung Cancer) 07/2023 - 11/2014
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020 - 02/2014
4	Idiopathic Pulmonary Fibrosis 10/2022 - 12/2013
3	Prostatic Neoplasms (Prostate Cancer) 01/2024 - 06/2023
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2023 - 11/2022
3	Neoplasm Metastasis (Metastasis) 07/2023 - 11/2014
2	Cerebral Hemorrhage 03/2024 - 07/2023
2	Adenocarcinoma of Lung 12/2023 - 10/2018
2	Congenital Heart Defects (Congenital Heart Defect) 11/2023 - 02/2023
2	Familial Primary Pulmonary Hypertension 11/2023 - 02/2023
2	Hypoxia (Hypoxemia) 01/2022 - 10/2016
2	Pulmonary Hypertension 01/2022 - 10/2016
2	Vascular Remodeling 01/2022 - 10/2016
2	Emphysema 09/2021 - 01/2020
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 01/2020
2	Virus Diseases (Viral Diseases) 01/2021 - 03/2020
2	Edema (Dropsy) 12/2019 - 08/2011
2	Hyperoxia 06/2011 - 05/2009
1	Hematoma 03/2024
1	Brain Injuries (Brain Injury) 03/2024
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2024
1	Brain Edema (Cerebral Edema) 03/2024
1	Infarction (Infarctions) 01/2024
1	Glioma (Gliomas) 09/2023
1	Ischemic Stroke 09/2023
1	Lymphatic Metastasis 07/2023
1	Adenocarcinoma 01/2023
1	Hepatocellular Carcinoma (Hepatoma) 01/2023
1	Genomic Instability 01/2023
1	Kidney Calculi (Kidney Stone) 01/2023

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 03/2024 - 09/2009
13	CytokinesIBA 12/2019 - 02/2006
8	lysophosphatidic acidIBA 01/2021 - 03/2009
6	Biomarkers (Surrogate Marker)IBA 12/2023 - 07/2013
6	Bleomycin (Blenoxane)FDA LinkGeneric 10/2022 - 12/2013
6	UbiquitinIBA 01/2020 - 06/2012
6	Lysophosphatidic Acid ReceptorsIBA 08/2016 - 11/2009
5	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024 - 05/2009
5	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2021 - 08/2011
4	LipopolysaccharidesIBA 05/2024 - 10/2011
4	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2023 - 01/2011
4	EnzymesIBA 01/2021 - 07/2013
4	Interleukin-33IBA 08/2015 - 06/2012
4	Small Interfering RNA (siRNA)IBA 06/2014 - 04/2008
3	EndotoxinsIBA 02/2024 - 09/2009
3	Transcription Factors (Transcription Factor)IBA 11/2023 - 01/2016
3	LigandsIBA 07/2023 - 03/2020
3	Deubiquitinating EnzymesIBA 09/2021 - 07/2019
3	LipidsIBA 01/2021 - 10/2011
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2019
3	Ligases (Synthetase)IBA 01/2019 - 06/2012
3	Cadherins (E-Cadherin)IBA 11/2014 - 09/2009
3	F-Box ProteinsIBA 11/2013 - 06/2012
2	Fibronectins (Fibronectin)IBA 03/2024 - 01/2020
2	NF-kappa B (NF-kB)IBA 01/2023 - 01/2005
2	Tyrosine Kinase InhibitorsIBA 01/2023 - 01/2022
2	Semaxinib (SU5416)IBA 01/2022 - 10/2016
2	SmokeIBA 09/2021 - 01/2020
2	RNA (Ribonucleic Acid)IBA 01/2021 - 10/2018
2	CollagenIBA 01/2020 - 01/2016
2	Interleukin-1 (Interleukin 1)IBA 07/2019 - 01/2015
2	indium-bleomycinIBA 01/2018 - 07/2015
2	Histones (Histone)IBA 06/2017 - 01/2017
2	3- (4- (4- ((1- (2- chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acidIBA 07/2015 - 10/2011
2	ChemokinesIBA 10/2011 - 02/2006
2	Tyrosine (L-Tyrosine)FDA Link 05/2009 - 10/2003
2	1-dodecylpyridoxal (PLD)IBA 05/2009 - 10/2003
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 05/2024
1	indoleacetic acid (indole acetic acid)IBA 05/2024
1	GPR39-C3IBA 03/2024
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 03/2024
1	ThioredoxinsIBA 03/2024
1	N-(3,4,5-trichlorophenyl)succinimideIBA 01/2024
1	Blood Proteins (Serum Proteins)IBA 12/2023
1	Gemcitabine FDA Link 11/2023
1	N-methyladenosineIBA 09/2023
1	NaoluoxintongIBA 09/2023
1	AntibodiesIBA 07/2023
1	Immunoglobulin G (IgG)IBA 07/2023
1	Immunoglobulin M (IgM)IBA 07/2023
1	AutoantibodiesIBA 07/2023
1	lenvatinibIBA 01/2023
1	NucleotidesIBA 01/2023
1	RELTIBA 01/2023
1	Complement System Proteins (Complement)IBA 01/2023
1	Leucine-Rich Repeat ProteinsIBA 01/2023

Therapy/Procedure

7	Therapeutics 07/2023 - 03/2011
5	Radiotherapy 01/2024 - 03/2011
1	Decompressive Craniectomy 01/2024
1	Drug Therapy (Chemotherapy) 01/2023